On Fast and Robust Information Spreading in the Vertex-Congest Model

This paper initiates the study of the impact of failures on the fundamental problem of \emph{information spreading} in the Vertex-Congest model, in which in every round, each of the $n$ nodes sends the same $O(\log{n})$-bit message to all of its neighbors. Our contribution to coping with failures is twofold. First, we prove that the randomized algorithm which chooses uniformly at random the next message to forward is slow, requiring $\Omega(n/\sqrt{k})$ rounds on some graphs, which we denote by $G_{n,k}$, where $k$ is the vertex-connectivity. Second, we design a randomized algorithm that makes dynamic message choices, with probabilities that change over the execution. We prove that for $G_{n,k}$ it requires only a near-optimal number of $O(n\log^3{n}/k)$ rounds, despite a rate of $q=O(k/n\log^3{n})$ failures per round. Our technique of choosing probabilities that change according to the execution is of independent interest.Comment: Appears in SIROCCO 2015 conferenc

Ultrasonic characterization of the pulmonary venous wall: echographic and histological correlation

Background: Pulmonary vein isolation with radiofrequency catheter ablation techniques is used to prevent recurrences of human atrial fibrillation. Visualization of the architecture at the venoatrial junction could be crucial for these ablative techniques. Our study assesses the potential for intravascular ultrasound to provide this information. Methods and Results: We retrieved 32 pulmonary veins from 8 patients dying from noncardiac causes. We obtained cross-sectional intravascular ultrasound (IVUS) images with a 3.2F, 30-MHz ultrasound catheter at intervals on each vein. Histological cross-sections at the intervals allowed comparisons with ultrasonic images. The pulmonary venous wall at the venoatrial junction revealed a 3-layered ultrasonic pattern. The inner echogenic layer represents both endothelium and connective tissue of the media (mean maximal thickness, 1.4±0.3 mm). The middle hypoechogenic stratum corresponds to the sleeves of left atrial myocardium surrounding the external aspect of the venous media. This layer was thickest at the venoatrial junction (mean maximal thickness, 2.6±0.8 mm) and decreased toward the lung hilum. The outer echodense layer corresponds to fibro-fatty adventitial tissue (mean maximal thickness, 2.15±0.36 mm). We found a close agreement among the IVUS and histological measurements for maximal luminal diameter (mean difference, -0.12±1.3 mm) and maximal muscular thickness (mean difference, 0.17±0.13 mm) using the Bland and Altman method. Conclusions: Our experimental study demonstrates for the first time that IVUS images of the pulmonary veins can provide information on the distal limits and thickness of the myocardial sleeves and can be a valuable tool to help accurate targeting during ablative procedures

Analysis of measured stress data in a solid rocket motor

A sinusoidal regression model is fitted to stress and temperature response data in a solid rocket motor under various thermal loading conditions. Using the model statistics and measured failure data, failure probability and reliability calculations are performed for each loading condition via two different approaches

Genetic diversity of Neolamarckia cadamba using dominant DNA markers based on inter-simple sequence repeats (ISSRs) in Sarawak

Neolamarckia cadamba or commonly known as kelampayan has been selected as one of the important plantation tree species in Malaysia. Thus, the molecular characterization of this indigenous tropical tree species is needed to maintain its high quality. Inter simple sequence repeats (ISSR) markers were used in this study to determine the genetic diversity and relatedness of N. cadamba in two planted forests and six natural forests in Sarawak. Three ISSR primers had generated atotal of 239 loci, of which 32.6% - 59.4% of the loci were polymorphic among236N. cadamba treesin eight populations. The mean Shannon’s diversity index (I)ranged from 0.1399 to 0.2354. The coefficient of population differentiation was low for planted forests (Gst = 0.0871) and natural forests (Gst = 0.2013`). Both UPGMA dendrogram and NJ-tree generated by ISSR markers had divided natural forests and planted forests into two distinct clusters. Natural forests were grouped in one cluster while planted forests were grouped in another cluster. This study shows that N. cadamba trees are closely related within its own population and its designated forest type. In future, several specific loci can be sequenced and developed into SCAR (sequence characterized amplification region) markers for tree improvement and conservation programme of N. cadamba

Anisotropic conduction in the triangle of Koch of mammalian hearts: electrophysiologic and anatomic correlations

AbstractObjectives. The purpose of this study was to characterize anisotropy in the triangle of Koch by relating electrophysiology with anatomy.Background. Atrioventricular (AV) node fast and slow pathway characteristics have been suggested to be due to nonuniform anisotropy in the triangle of Koch.Methods. During atrial pacing, we determined the electrical activity within the triangle of Koch by multichannel mapping in 11 isolated hearts from pigs and dogs. Orientation of fibers was determined in nine hearts.Results. Fibers were parallel to the tricuspid valve annulus (TVA) in the posterior part of the triangle of Koch. In the midjunctional area, the direction of the fibers changed to an orientation perpendicular to the TVA. During stimulation from posterior and anterior sites, activation proceeded parallel to the TVA at a high conduction velocity (0.5 to 0.6 m/s). During stimulation from sites near the coronary sinus, a narrowzone of slow conduction occurred in the posterior part of the triangle of Koch where activation proceeded perpendicular to the fiber orientation. Above and below this zone, conduction was fast and parallel to the annulus. After premature stimulation, conduction delay in the triangle of Koch increased by 4 to 21 ms; in contrast, the AH interval increased by 80 to 210 ms.Conclusions. Data support the concept of anisotropic conduction in the triangle of Koch. Activation maps correlated well with the arrangement of superficial atrial fibers. Comparison of conduction delay in the triangle of Koch and AH delay after premature stimulation disproves that anisotropy in the superficial layers plays an important role in slow AV conduction

Termoreverzibilni mukoadhezivni in situ hidrogel za oftalmičku primjenu: dizajniranje i optimizacija koristeći kombinaciju polimera

The purpose of the study was to develop an optimized thermoreversible in situ gelling ophthalmic drug delivery system based on Pluronic F 127, containing moxifloxacin hydrochloride as a model drug. A 32 full factorial design was employed with two polymers Pluronic F 68 and Gelrite as independent variables used in combination with Pluronic F 127. Gelation temperature, gel strength, bioadhesion force, viscosity and in vitro drug release after 1 and 10 h were selected as dependent variables. Pluronic F 68 loading with Pluronic F 127 was found to have a significant effect on gelation temperature of the formulation and to be of importance for gel formation at temperatures 3336 ºC. Gelrite loading showed a positive effect on bioadhesion force and gel strength and was also found helpful in controling the release rate of the drug. The quadratic mathematical model developed is applicable to predicting formulations with desired gelation temperature, gel strength, bioadhesion force and drug release properties.Cilj rada bio je razvoj i optimizacija termoreverzibilnog sustava za isporuku lijekova koji gelira in situ. Sustav je napravljen na bazi Pluronic F 127, a sadrži moksifloksacin hidroklorid kao modelni lijek. U radu je primjenjeno 32 potpuno faktorijsko dizajniranje s dva polimera, Pluronic F 68 i Gelrite kao nezavisnim varijablama koji su kombinirani s Pluronic F 127. Kao zavisne varijable odabrane su temperatura geliranja, čvrstoća gela, jačina bioadhezije, viskoznost i in vitro oslobađanje lijeka nakon 1 i 10 h. Pronađeno je da Pluronic F 68 u kombinaciji s Pluronic F 127 ima značajan učinak na temperaturu geliranja u rasponu od 33 do 36 C. S druge strane, Gelrite ima povoljan učinak na jačinu bioadhezije, čvrstoću gela i oslobađanje lijeka. Razvijen je kvadratni matematički model pomoću kojeg se može predvidjeti temperatura geliranja, čvrstoća gela, jačina bioadhezije i oslobađanje ljekovite tvari

Development and validation of measures to study the effects of the built environment on walking in Hong Kong older adults

Conference Theme: Age-friendly Cities with Cooperation & Participatio

Effects of built environment on walking among Hong Kong older adults

 Key Messages1. Reliable and valid intervieweradministered questionnaires were developed to investigate associations of perceived neighbourhood attributes of Hong Kong older adults with their walking for transportation and recreation.2. Access to and availability of different types of services and destinations, provision offacilities for resting/sitting in the neighbourhood, and easy access to/from residentialbuildings may help maintain an active lifestyle by facilitating walking for transport in the neighbourhood.3. Access to services, indoor places for walking, environmental aesthetics, low traffic, and absence of physical barriers may promote recreational walking